Oh et al. performed a high-throughput kinase binding assay and identified that PI3K, AKT and mTOR might not be directly affected by fascaplysin, whereas multiple types of cancer-related kinases, such as VEGFR3, VEGFR2 and TRKA, were inhibited by fascaplysin at concentrations lower than 3 μM. The gene discussed is AKT1; the disease is cancer.