There were no other imbalances between the two groups in terms of age (p = 0.374), gender (p = 0.530), LDH (p = 0.739), cancer stage (p = 1.000), number of metastatic sites (p = 0.184), baseline brain metastasis (p = 0.397), BRAF-mutation subtypes (p = 0.326), received palliative RT (p = 1.000), or received palliative surgery (p = 0.532). The gene discussed is BRAF; the disease is cancer.