CD274 and neoplasm: In addition, the benefit of nivolumab was greater in patients with expression of the ligand of the targeted receptor, PD-L1 in more than 1% of tumor cells (HR: 0.56, 95% confidence interval: 0.40–0.80 versus HR: 0.82, 95% confidence interval: 0.63–1.06 in patients with PD-L1 less than 1%) [2].