In a study of lung inflammation under sepsis conditions, Pedrazza et al. found that co-culture of MSCs from epididymal adipose tissue with RAW cells could lead to a significant decrease in TNF-α and IL-6 (pro-inflammatory cytokines) and a significant increase in IL-10 (anti-inflammatory cytokines) when the cells were challenged with LPS at different time points [41]. The gene discussed is IL10; the disease is Sepsis.