It was obviously observed from western blot results and immunofluorescent images that the suppressive impact of HE on the cell viability and fibrosis was partially abated by pilocarpine, as evidenced by increased cell viability, Col-I and Col-III, and α-SMA expression after pilocarpine treatment (Figure 9(b-d)). This evidence concerns the gene ACTA1 and hereditary elliptocytosis.