CNR1 and glioblastoma: In this context, as discussed above, engagement of an unambiguous molecular target (CB1R/CB2R) by a family of selective compounds (THC and other cannabinoid receptor agonists) efficaciously inhibits the growth of grafted glioblastoma cells in animal (mouse and rat) models through a defined mode of anti‐tumoral action (Luís et al., 2020; Rocha et al., 2014).