Enforced expression of Gmnc or Mcidas led to the formation of multiple cilia and reduced proliferation in infected tumor cells within 72 h (Fig. 7C, D; Supplementary Fig. S12A, B), phenocopying NOTCH inhibition with IMR-1 that significantly increased Gmnc levels in tumor cells (Fig. 7E). This evidence concerns the gene MCIDAS and neoplasm.