Comparison between LC and CHC patients showed a higher mean value of ALT (P < 0.001), AST (P < 0.001), γGT (P < 0.0001), α-Fetoprotein (P < 0.001), in total Bilirubin (P < 0.001), in INR (P < 0.001), in BUN (P = 0.0011) and a lower mean value of Triglycerides (P < 0.0001) and in Albumin (P < 0.001). The gene discussed is GPT; the disease is cryohydrocytosis.