The comparison between HCC and CHC subjects showed a higher mean value in ALT (P = 0.01), in AST (P < 0.001), in γGT (P < 0.0001), in Total Bilirubin (P < 0.001), in α-Fetoprotein (P < 0.001), in BUN (P < 0.0001), in INR (P < 0.001), and a lower mean value in Total Cholesterol (P < 0.0001), in albumin(P < 0.001), in fasting glucose (P < 0.0001) and in serum creatinine (P = 0.0334). The gene discussed is GPT; the disease is cryohydrocytosis.