FMR1 and neurodevelopmental disorder: Fragile X syndrome (FXS, OMIM 300624), a neurodevelopmental disorder characterized by intellectual disability and autism, is caused by a mutation in the fragile X mental retardation 1 (FMR1) gene located on the X chromosome at Xq27.3 wherein a DNA segment, known as the CGG triplet is expanded within the 5′ untranslated region (5′ UTR) of FMR1 gene1.