KIFAP3 and adenocarcinoma: We confirmed that KAP3 expression, at both the protein and mRNA levels, was decreased in NUGC4 and KATOIII cells compared with cell lines derived from other histological subtypes of GC (i.e., tubular adenocarcinoma, MKN7 and MNK74 cells; poorly differentiated adenocarcinoma, MNK45 and NUGC3 cells), as determined by immunoblot and qRT-PCR analysis (Fig. 1A,B).