COL1A1 and liver cancer: Based on the analysis of 367 liver cancer patients from The Cancer Proteome Atlas (TCGA) database, the COL1A1 and COL1A2 signatures showed modest correlation with ITGA2 (R = 0.49, p < 2.2e-16, R = 0.51, p < 1.7e-12, Pearson’s correlation) (Fig. 4E).