RELA and Peritoneal Fibrosis: Reminiscent of the key features of PDF-elicited peritoneal fibrosis, hypertonic dextrose elicited considerable profibrotic changes, inflammatory reaction and oxidative damage in control empty vector-transfected PMC cultures, marked, respectively, by fibronectin overexpression, increased phosphorylation and activation of NFκB RelA/p65, and induction of nitrotyrosine, concomitant with an antioxidant self-defense as evidenced by increased nuclear expression of Nrf2.