DDIT3 and cancer: In malignant hematological cancer, Spatholobus suberectus Dunn, Salvia miltiorrhiza, and Cnidium officinale Makino showed an anti-cancer effect via regulation of miR-657/ATF-2, miR-216b/c-Jun, and miR-211/CHOP, respectively (16a) (31, 32).