Several studies have revealed the anti-cancer effect of a Sophorae Flos and Lonicerae japonicae Flos-regulated miR-let-7/f-CCR7 network (74), SSD-regulated miR-657/ATF2 network (16), SM-regulated miR-216b/c-Jun network (32), COM extract-regulated miR-211/CHOP network (31), and Panax ginseng C.A. Meyer (Rg3)-regulated miR-21/PI3K/AKT network (75). This evidence concerns the gene ATF2 and cancer.