Because the number of CXCL8 in gastric carcinomas may be influenced by some clinicopathological parameters (such as histology, TNM staging), to minimize the selection bias, 70 EBVaGC cases and 62 EBVnGC cases with matched clinicopathological parameters were selected for further investigation of CXCL8 and prognosis in the present study. This evidence concerns the gene CXCL8 and gastric carcinoma.