ACE2 and viral infectious disease: Given that angiotensin-converting enzyme 2 (ACE2) has an important regulatory role in the RAS and has been identified as the functional receptor by which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters human cells,8 we hypothesized that this enzyme could also be part of the CB local RAS and thus make CB cells a potential target for SARS-CoV-2 viral infection.