TARDBP and proteostasis deficiencies: A more recent study using RNA immunoprecipitation assays, TRAP, and bioinformatics analyses, reported the glypican Dally like protein (Dlp) as a novel TDP-43 candidate target, based on the enrichment of dlp mRNA in TDP-43 complexes and depletion from ribosomes in the context of TDP-43 proteinopathy (Lehmkuhl et al., 2021).