CLOCK and inflammatory bowel disease: Based on the results of the above-mentioned existing studies, thinking about how to use the circadian rhythm to maintain the homeostasis of bile acid metabolism, letting the body's metabolite bile acid play an anti-inflammatory effect, and then managing IBD is the most economical and safest treatment strategy, which is worth designing In-depth research on basic and clinical experiments is carried out to develop a new regimen of maintaining bile acid metabolism homeostasis combined with circadian clock therapy for the treatment of IBD.