Of note, the data in Figure 4A showed that Ang-II induced AAA (28 days) upregulated 4.51% canonical secretome, 1.04% caspase 1 secretome, 3.03% caspase 4 secretome, 3.67% exosome secretome, 10.81% WPB secretome, and 6.25% autophagy secretome, respectively. This evidence concerns the gene CASP1 and triple-A syndrome.