IL6 and neoplasm: As shown in Figure 5B, canonical SGs in elastase induced AAA aortas had functional pathways of IL-17 signaling, differential regulation of cytokine production by IL-17A and IL-17F, IL-6 signaling, tumor microenvironment pathway, acute phase response, TREM1 signaling, systemic lupus erythematosus in B cell signaling, crosstalk between dendritic cells and natural killer cells, role of hypercytokinemia/hyperchemokinemia, and dendritic cell maturation.