In AAA, 10 cytokines/interactors were upregulated in canonical secretome, no cytokines/interactors were upregulated in caspase 1 secretome, no cytokines/interactors were upregulated in caspase 4 secretome, three cytokines/interactors were upregulated in exosome secretome, two cytokines/interactors were upregulated in WBP, and one cytokine/interactor was upregulated in autophagy. Here, CASP1 is linked to triple-A syndrome.