Caspase 1 SGs at day 7 AAA aortas had functional pathways, namely, epithelial adherens junction signaling, integrin signaling, estrogen receptor signaling, phagosome formation, Fcγ receptor-mediated phagocytosis in macrophages and monocytes, actin cytoskeleton signaling, and insulin secretion signaling. This evidence concerns the gene ESR1 and triple-A syndrome.