Research related to autoimmune hepatitis (AIH) has shown that serum BAFF levels are significantly higher in patients with AIH, compared to hepatitis patients and healthy controls, with positive correlations to AST, ALT, TBIL, and soluble CD30, implying BAFF contributes to liver injury in patients with AIH (26). The gene discussed is TNFRSF8; the disease is autoimmune hepatitis.