CD4 and colitis: In particular, L. reuteri treatment reduced the number of CD11b+CD11c+ dendritic cells (DCs) (Figure 2D, p < 0.05), a major source of pro-inflammatory cytokines during colitis, whereas the number of Foxp3+CD4+ T cells in MLNs was increased compared to the DSS-only group (Figure 2E, p < 0.001).