14 Silverio Silverio JC JC Pereira Pereira IR IR Cipitelli Cipitelli MC MC Vinagre Vinagre NF NF Rodrigues Rodrigues MM MM Gazzinelli Gazzinelli RT RT CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy PLoS Pathog PLoS Pathog 2012 2012 8 8 4 4 e1002645 e1002645 22532799 22532799. The gene discussed is PRF1; the disease is cardiomyopathy.