RPS6KB1 and coronary artery disorder: Moreover, although the phosphorylation levels of 4EBP1 and S6K, which are indicators of cellular protein translation, were higher in the embryonic heart tissues obtained from high‐leucine diet‐fed mice than in those obtained from normal‐chow‐fed mice (Figure 1E), we excluded the possibility that altered protein translation could contribute to the CHD onset because the other two types of branched‐chain amino acid activated 4EBP1 and S6K but did not cause CHD in mice (Figure S4, Supporting Information).