WDR81 and Reoviridae infectious disease: To ensure that the observed defect in reovirus infection was due to the genetic ablation of WDR81, we transduced ΔWDR81 cells with an empty lentivirus or a lentivirus that confers expression of 2xHA-tagged human WDR81 (hu-WDR81), which shares 88% homology with murine WDR81.