NF‐κB, a key transcription factor, is known to regulate the expression of many genes involved in the immune response, inflammation, viral infection, and programmed cell death.[39] Phosphorylation by inhibitor of nuclear factor NF‐κB (IκB) kinase (IKK) promotes the ubiquitylation and proteasomal targeting of IκB, which allows NF‐κB to translocate to the nucleus and initiate transcription. The gene discussed is NFKB1; the disease is viral infectious disease.