Also, ACE inhibition provoked areduction in the observed parameters between the C57BL/6 groups: VLF (3.9±0.1vs 20.2±2.7 ms in the saline group, P<0.0001), LF(3.6±1.0 vs 14.6±6 ms, P=0.0001), and HF (1.2±0.2vs 8.6±0.8, P<0.0001). The gene discussed is ACE; the disease is hydrops fetalis.