Major Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) JAMA JAMA 2002 2002 288 288 23 23 2981 2981 2997 2997 10.1001/jama.288.23.2981. Here, ACE is linked to myocardial infarction.