For adults with craniopharyngioma and pituitary adenomas, a waiting period of 12 months was discussed in order to secure adequate evaluation of GHD treatment and diagnosis, but consensus was not reached on this and some experts considered it safe to start GH replacement after pituitary surgery for craniopharyngiomas or for benign pituitary adenomas without a waiting period as long as other pituitary hormone deficiencies are adequately replaced. The gene discussed is GH1; the disease is hypopituitarism.