PML and infection: By correlative light and electron microscopy (TEM and FIB-SEM tomography), we identify PML cages as circular clusters of viral capsids that are enveloped by PML fibers and occur after high MOI infection with HCMVΔIE1 (Figure 7c–e; Figure 7—figure supplement 3), but not wild-type HCMV (Figure 7—figure supplement 2S).