Many neurodegenerative diseases are connected to defects in OxPhos (Koopman et al, 2013) or PGC‐1 (Cui et al, 2006; Zheng et al, 2010); examining if mutating AtosA in neurons results in lower levels of mitochondrial OxPhos, and decreased neural survival and signaling will be an interesting area of inquiry. The gene discussed is PPARGC1A; the disease is neurodegenerative disease.