Our findings underscore this point by demonstrating that CSF levels of CXCL13 are below the proposed 162 pg/mL diagnostic cutoff (26) in most patients with suspected LNB (median CXCL13 levels 1 pg/mL) and even in many patients with PFP/meningitis (median CXCL13 levels 53 pg/mL). Here, CXCL13 is linked to infectious meningitis.