For serum biochemical variables, 78.3% (n = 47), 96.7% (n = 58), and 43.3% (n = 26) had increases in ALT, ALP, GGT activities above the reference interval, respectively, and 63.3% (n = 38) dogs had hyperbilirubinemia. The gene discussed is GPT; the disease is Hyperbilirubinemia.