Through multivariable logistic analysis, Song et al. also showed that CRP levels were associated with an increased risk of in-hospital mortality (OR 2.467, 95% CI 1.030–5.911, P = 0.043) and reduced P/F ratio (OR 0.989, 95% CI 0.983–0.996, P = 0.001) in patients with AE of IPF (n = 96)4. The gene discussed is CRP; the disease is idiopathic pulmonary fibrosis.