These tended to decrease at 1-month post-infection (T-bethi switched IgM; average 2.93%; SEM 0.77% and unswitched MBCs; average 12.34%; SEM 3.49%) and continued to decline over subsequent timepoints, indicating that T-bethi unswitched MBCs were likely switched into T-bethi IgG MBCs after infection (Fig. 3b and Supplementary Fig. 2). Here, CD40LG is linked to infection.