Differential gene expression analysis between breast cancer patients (n = 2509) with high and low GIT1 levels revealed significantly increased expression of aldehyde dehydrogenase 1 (ALDH1) and C-X-C chemokine receptor type 4 (CXCR4) in the patients with low GIT1 (Fig. 2e). The gene discussed is CXCR4; the disease is breast carcinoma.