AKT1 and viral myocarditis: Up-regulated genes were enriched in 19 pathways, including “focal adhesion”, “PI3K-Akt signaling”, “NOD-like receptor signaling”, “ECM-receptor interaction”, “Toll-like receptor signaling”, etc. Down-regulated genes were significantly enriched in two pathways; “metabolic” and “viral myocarditis” (Fig. 1D, E).