NORAD and pachyonychia congenita: To appreciate the transcriptome-wide implications of miR-346 and NORAD activity in advanced PC, we performed RNA-seq analysis of C42/miR-346 and C42/shNORAD (stably expressing miR-346 and shNORAD, respectively, under doxycycline control) cells ±Dox, and also C42 cells transiently transfected with siNORAD or negative control siRNA (siNC).