PUM1 and pachyonychia congenita: To investigate the relevance of PUM2 for NORAD function in PC, we assessed the relationship between NORAD and PUM2 expression in publicly-available RNA-seq datasets: NORAD expression significantly correlated with PUM2 in both localised PC (Fig. S8B) and mCRPC (Fig. 3B), and also with PUM1 (Fig. S8C).