Luo et al. (2019) used chondroitin sulfate nanomicelles (CSmicelles) to target HSCs by binding with CD44, and retinoic acid (RA) and doxorubicin (DOX) were encapsulated to mediate specific cytotoxicity toward HSCs to alleviate liver fibrosis. This evidence concerns the gene CD44 and Hepatic fibrosis.