KDM1A and acute myeloid leukemia: The introduction of a phenyl ring at the para position of the MC2584 benzoylamino moiety led to MC2652 (1a) (Figure 1), less potent in LSD1 inhibition but more selective towards MAOs, and able to arrest MV4-11 acute myeloid leukaemia (AML) and NB4 APL cell growth with IC50 values at low, single-digit micromolar levels.25