There are studies evaluating the refractive outcome in the advanced ages of premature infants with or without severe ROP.[5-7] Refractive problems such as anisometropia, myopia, and astigmatism have been shown widely in children who were born prematurely.[5] There are studies evaluating the effect of LPC and anti-VEGF treatments on refractive outcomes.[8,9]. Here, VEGFA is linked to retinopathy of prematurity.