PPARG and obesity due to melanocortin 4 receptor deficiency: Another clinical trial explained that administration of green cardamom (3 g/day, 16 weeks) controlled the expression of some diabetes and obesity genes including fat mass and obesity-associated (FTO), carnitine palmitoyltransferase 1A (CPT1A), leptin receptor (LEPR), lamin A/C, and peroxisome proliferator-activated receptor gamma (PPAR-γ) in women with polycystic ovary syndrome (67).