Moreover, expression of CCR5 (ligands CCL3, CCL4, and CCL5), CCR4 (ligands CCL17 and CCL22), and CCR3 (ligands eotaxin and eotaxin-2) on different immune cells is associated with the progress of inflammation in SLE (11, 12). Here, CCR3 is linked to systemic lupus erythematosus.