In the present study, we investigated the expression of chemokine receptors, CXCR3, CCR5, CCR4, and CCR3, in the surface of probiotic-maturated tolerogenic DCs (matured by L. rhamnosus and L. delbrueckii) with monocyte origin to find the effect of these probiotics on migratory lupus-DC patterns. Here, CCR3 is linked to systemic lupus erythematosus.