Based on the TCGA-BRCA dataset, our results showed that the low expression levels of ADIPOQ (HR = 0.4, p < 0.001), IGF1 (HR = 0.529, p < 0.05), LEP (HR = 0.535, p < 0.05), NR3C1 (HR = 0.549, p < 0.05), and PPARG (HR = 0.464, p < 0.01) were significantly associated with the worse OS of breast cancer patients with tumor pathological stages III–IV (Figures 6F–J). This evidence concerns the gene ADIPOQ and breast cancer.