ASPN and osteoarthritis: A similar trend is found for asporin, with a higherrelative abundance in the inhumed cadavers than in the other group.Asporin is involved in cartilage and bone degeneration and plays arole in the insurgence of osteoarthritis.45 Similarly to lactadherin, also in this case, there is a significantnegative correlation between its abundance and age (Supplementary Table S2); therefore, for the same reason previouslyexplained, the notion that the deposition type caused the observeddifferences in the relative abundances among the two groups can beexcluded.