CAD and infection: The program that we used for our virtual screen, PLANTS, itself has been cited in studies aiming to identify therapeutics for a variety of infections including targeting of DNA gyrase B in E. coli [48], the HIV-1 integrase strand transfer complex [49], dihydroorotase in S. aureus [50], and most recently there has been a significant effort to target the main protease (Mpro) of SARS-CoV-2 [51–53].