CD11c+CD68+CD163+ APCs were the immune population found to be preferentially enriched in gliomas relative to metastases, irrespective of the tumor compartment being considered (edge, P = 0.0311; tumor, P = 0.0003; necrosis, P = 0.0007) (Figure 2, B–D). This evidence concerns the gene CD68 and central nervous system cancer.