MTs have been observed to participate in a series of cellular processes, such as redox and metal homeostasis, immunomodulation, anti-inflammatory reactions, and tumor development and progression.4,5,7,20–22 In this research, through the analysis of ONCOMINE database, we found distinct differences in MT1F, MT1G, MT1H, MT1X expression in normal group and AML group. The gene discussed is MT1H; the disease is acute myeloid leukemia.