MCAT and acute myeloid leukemia: Duval et al. showed that overexpression of MT1 prevented apoptosis of embryonic stem cell-derived differentiated cells.13 Maghdooni Bagheri et al. revealed that the more mature hematopoietic precursor cell lines K562, DAMI, and MEG01 cells had higher MT levels than the immature ELF153 cells.14 Overexpression of MT2A in megakaryocytic DAMI cells caused increases in the cell size, intracellular granulation, and levels of megakaryocytic-specific CD41 and CD42 with arrest of cell proliferation.15 MT was expressed in leukemic cells from 68% of cases with newly diagnosed AML.