The levels of MT expression in the relapse patients were higher than those in the remission patients.16 The expressions of the MT1A and MT1G genes were significantly inversely correlated with the hematopoietic transcription factor PU.1 gene in 43 primary acute AML specimens.17 These studies indicated that increased MTs expression represented a poor prognostic marker for AML. This evidence concerns the gene MT1A and acute myeloid leukemia.