The results of CCK8 (Figure 5(b)) and flow cytometry (Figure 5(d)) assays displayed that compared with the NC group, the upregulation of miR-376a-3p significantly inhibited proliferation and induces apoptosis of THP1 cells, while overexpressed MT1X would attenuate the inhibitory effects of miR-376a-3p overexpression in AML cells. The gene discussed is MT1X; the disease is acute myeloid leukemia.