While the International Neuroblastoma Risk Group (INRG) analyzed 8800 childhood NB patients and identified seven potential prognostic factors to category patients into very low, low, intermediate, and high‐risk diseases, which including age, INRG stage, tumor differentiation grade, histologic subtypes, absence/presence of 11q aberrations, MYCN status, and tumor cell ploidy.6, 7. This evidence concerns the gene MYCN and neuroblastoma.