A very recent systematic review and meta-analysis of RCTs showed that a diet with a low GI/GL compared to higher GI/GL control diets (Median low vs. high: GI 49 vs 63 and GL 102 vs. 138) in overweight and obese patients with T1DM and T2DM reduced HbA1c-level, fasting glucose, but not blood insulin [40], indicating that a diet with a low GI/GL can be useful for overweight and obese patients with T2DM. Here, INS is linked to type 2 diabetes mellitus.