PLIN2 and gastric cancer: Another study showed that PLIN2 promotes the proliferation and apoptosis of gastric cancer cells by modifying the ferroptosis pathway, such as regulating various ferroptosis-related genes, including acyl-CoA synthase long-chain family member 3, etc. PLIN2 has also been shown to be an indispensable factors for inhibiting ferroptosis caused by abnormal fat metabolism in gastric cancer49.