INS and diabetes mellitus: Sensitivity analysis was conducted under the condition that we used multiple-imputation method to impute the missing data of the duration of diabetes, insulin injection, eGFR, ACR, HDL-C, retinopathy, TG, FPG variation, HbA1c variation, and hypertension drug use, resulting in the inclusion of 7,552 subjects in our risk model to validate the model performance.